BEGIN:VCALENDAR PRODID:-//Microsoft Corporation//Outlook 16.0 MIMEDIR//EN VERSION:2.0 METHOD:PUBLISH X-MS-OLK-FORCEINSPECTOROPEN:TRUE BEGIN:VTIMEZONE TZID:GMT Standard Time BEGIN:STANDARD DTSTART:16011028T020000 RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=10 TZOFFSETFROM:+0100 TZOFFSETTO:-0000 END:STANDARD BEGIN:DAYLIGHT DTSTART:16010325T010000 RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3 TZOFFSETFROM:-0000 TZOFFSETTO:+0100 END:DAYLIGHT END:VTIMEZONE BEGIN:VEVENT CATEGORIES:Stage 4 CLASS:PUBLIC CREATED:20250512T100944Z DESCRIPTION:Presentation:\nDesigning\, Scaling-up and Troubleshooting Mixin g Processes\n \nSpeaker:\nDavid Brown - Mixing and Process Engineering Man ager - Framatome Limited\n \nAbout this Presentation\nAn overview of the k ey considerations and common methods to design\, scale-up (and down) and t roubleshoot mixing processes. This includes the transfer of specific proce sses between different manufacturing facilities and methods\, and establis hing the potential for transferring batch or semi-batch process to continu ous operation.\n* Background knowledge on process and controlling phenomen a. The critical starting point\, and too frequently ignored or under-consi dered.\n* Correlation and mechanistic models. Awareness and application of these models\, and consideration of their safe application under conditio ns outside where they were developed\n* Use of mixing specific software. S oftware tools have the potential to significantly speed up calculations\, but also they can hide the background to calculations and be easy to miss- apply. They also do not factor in or give guidance on any uncertainties in their application or confidence intervals in the results.\n* CFD and othe r more complex modelling tools\n \nDavid Brown - Chemical UK Expo \n \n \n \n DTEND;TZID="GMT Standard Time":20250521T140000 DTSTAMP:20250512T100944Z DTSTART;TZID="GMT Standard Time":20250521T134000 LAST-MODIFIED:20250512T100944Z LOCATION:Stage 4 PRIORITY:5 SEQUENCE:0 SUMMARY;LANGUAGE=en-gb:Presentation: Designing\, Scaling-up and Troubleshoo ting Mixing Processes TRANSP:OPAQUE UID:040000008200E00074C5B7101A82E00800000000E0CEA89CF9C0DB01000000000000000 01000000005EE63A634F77D479B3FCAEE4C49407D X-ALT-DESC;FMTTYPE=text/html:

Presentation:

Designing\, Scaling -up and Troubleshooting Mixing Processes

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Speaker:

David Brown - Mixing and Process Engineering Manager - Framatome Limited

 \;

About this Presentation

An overview of the key considerations and common methods to desig n\, scale-up (and down) and troubleshoot mixing processes. This includes t he transfer of specific processes between different manufacturing faciliti es and methods\, and establishing the potential for transferring batch or semi-batch process to continuous operation.

  • Background knowledge on process and controlling phenomena. The critic al starting point\, and too frequently ignored or under-considered.
  • Correlation and mechanistic models. Awareness and application of these mod els\, and consideration of their safe application under conditions outside where they were developed
  • Use of mixing specific software. Software tools have the potential to significantly speed up calculations\, but also they can hide the background to calculations an d be easy to miss-apply. They also do not factor in or give guidance on an y uncertainties in their application or confidence intervals in the result s.
  • CFD and other more complex modelling tools

 \;

David Brown - Chemic al UK Expo

 \;

 \;

 \;

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